Is DNA Polymerase an Enzyme? 9 Facts (Read This First!)


DNA is said to be the genetic material that is hereditary in the humans and in almost all of the rest organism. DNA and ribonucleic acid are nucleic acids

DNA polymerase is an enzyme that tends to fasten the synthesis of DNA at the time of replication. It adds nucleotides to the 3’ by one at a time. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

They also make the molecules of DNA by having the nucleotide assembled that are termed as the building blocks of DNA. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis. These are said to be vital for the replication of DNA and tends to work in pairs making identical strands of DNA.

It is an enzyme that helps in making of the new copies of the DNA in the form of molecules of nucleic acid. It can be said that it helps in having the cells of the DNA duplicated. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis. The protein called helicase is also involved with this.

Why is DNA polymerase an enzyme?

DNA polymerases are one of those that make the molecules and DNA. They work in pair making a DNA.

They make the identical strands of DNA from a single original molecule of DNA. At this method, this enzyme reads the already present DNA strands to make 2 of the new ones that shall match the already present ones. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

They do help in the duplication of the cell DNA so that there is a copy present of the original molecule that shall be passes to each of the daughter cell. In this manner, the gene material can be made to transfer from parents to daughter cell. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

is DNA polymerase an enzyme
Image credit-DNA polymeraseWikipedia

How is DNA polymerase an enzyme?

The genetic material is made to transfer from generation to generation. Thus polymerase is much vital for this method.

Before the completion of the process, there is an enzyme called the helicase that tends to unwind the molecule of DNA from the form which has been woven tight Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

Helicase tends to unzip this tight form to gives two separate strands of the DNA that shall be used up as templates in the method of DNA replication. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis. Polymerase adds up new nucleotides to the 3’ end making a new one.

These enzymes work together to open up the DNA strand in replication bubbles and copy the DNA strands semi-conservatively. The four main enzymes involved in DNA replication are DNA helicase, RNA primase, DNA polymerase, and DNA ligase.

What kind of enzyme is DNA polymerase?

As said earlier, it is the one that makes new copies of DNA in the manner that makes the molecules of nucleic acid. The power of it is used to also make DNA in lab via polymerase chain reaction

DNA polymerase can be called as primary enzymes. Nucleic acid are the polymers that are larger in size and is made up of smaller ones that keep repeating itself and are linked via chemicals to each other. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

They can be called as the primary enzyme that shall be able to synthesize the DNA and help with the replication process so that the genetic material can be transferred from one generation to the other which is vital for all of the living beings. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.                  

Where is DNA polymerase enzyme found?

There are 2 types of organism present that is distinguished by the number of cells present and they are the eukaryotes and prokaryotes.

This enzyme helping in replication is seen in all of the eukaryotes and are 5 in its type being the alpha, gamma, beta, δ, and ε. Gamma is seen in the mitochondria and rest are seen in the nucleus. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

This enzyme is said to be rooted from the discovery of an enzyme that has been extracted from the potatoes and shall help in the synthesis of the NAD which is the coenzyme seen in all of the living cells. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

These are the enzyme that make the molecule of DNA by gathering of all the nucleotides termed to be vital for building of the DNA bases. They are much vital for replication and mostly seen in pairs making identical forms. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

Image credit-NADWikipedia

Functions of DNA polymerase enzyme

The three different roles played by DNA polymerase are polymerisation, repair and proofreading. Enzymes are proteins that help speed up metabolism, or the chemical reactions in our bodies.

There are several forms of DNA polymerase that play a role in DNA replication and they usually work in pairs to copy one molecule of double-stranded DNA into two new double stranded DNA molecules. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis. The functions are-

  • Contributes to connecting Okazaki fragments
  • Deleting RNA primers and replacing the ribonucleotides with DNA
  • DNA replication
  • Ensure the maintenance of the genetic information
  • DNA polymerization
  • Faithful transmission through generations.

The DNA copies are created by the pairing of nucleotides to bases present on each strand of the original DNA molecule. This pairing always occurs in specific combinations, with cytosine along with guanine, and thymine along with adenine, forming two separate pairs, respectively. By contrast, RNA polymerases synthesize RNA from ribonucleotides from either RNA or DNA. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

Many DNA polymerases contain an exonuclease domain, which acts in detecting base pair mismatches and further performs in the removal of the incorrect nucleotide to be replaced by the correct one. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

Structure of DNA polymerase enzyme

Nucleic acids are polymers, which are large molecules made up of smaller, repeating units that are chemically connected to one another.

DNA polymerase pol β is a small eukaryotic DNA polymerase composed of two domains. Each domain contributes an enzymatic activity DNA synthesis and deoxyribose phosphate lyase during the repair of simple base lesions. These domains are termed the polymerase and lyase domains, respectively. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

The basic structure of all DNA polymerases consists of subdomains referred to as the palm, fingers, and thumb and resemble an open right hand. The palm contains catalytically essential amino acids in it’s active sites. The fingers are essential for nucleotide recognition and binding. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

Is DNA polymerase a protein?

DNA polymerase is defined as an enzyme. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

All of the enzymes are portions but all proteins are not enzymes. It adds the nucleotides one at a time with having its DNA duplicated. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis. Thus it helps in copying of the DNA from parent to offspring.

It is not basically defined to be a portion yet are made up of protein that are complex molecules and are in form of subunits. Thus it is an enzyme as well. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis. At this time, the data stored in the DNA s copied in the new molecule of the messenger RNA.

In simple words it can be automatically concluded that this enzyme is primary and thus helps in canalizing of the method which is true to the work of any enzymes and links the 3’ hydroxyl troop to the nucleotide end binding it with the 5’ phosphate troop that adds to it. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

Image credit-ProteinWikipedia

What is important about DNA polymerase enzyme?

 It is an important process to maintain and transfer genetic information from one generation to another.

DNA polymerase works in pairs, replicating two strands of DNA in tandem. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis. DNA polymerases are enzymes that create DNA molecules by assembling nucleotides, the building blocks of DNA

These enzymes are essential to DNA replication and usually work in pairs to create two identical DNA strands from one original DNA molecule. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis. Pol α initiates DNA synthesis on both the leading and lagging strands by synthesizing a RNA/DNA hybrid primer.

How DNA polymerase is produced and when?

It does this with the help of another enzyme, called helicase, which unwinds the double helix structure of the DNA molecule into two single DNA strands.

Either the individual proteins or the protein complex that assemble to form the active DNA polymerase, which acts in the nucleus, must enter the nucleus. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

DNA polymerases cannot synthesize DNA from a template strand. Synthesis must be initiated by a short RNA segment, known as RNA primer, synthesized by Primase in the 5′ to 3′ direction. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

Image credit-DNA replicationWikipedia

Conclusion

DNA polymerase is an enzyme that tends to fasten the synthesis of DNA at the time of replication. It adds nucleotides to the 3’ by one at a time. Thus with concern to the question is DNA polymerase an enzyme, yes it is an enzyme that helps in DNA synthesis.

ANKITA CHATTOPADHYAY

I am Ankita Chattopadhyay from Kharagpur. I have completed my B. Tech in Biotechnology from Amity University Kolkata. I am a Subject Matter Expert in Biotechnology. I have been keen in writing articles and also interested in Literature with having my writing published in a Biotech website and a book respectively. Along with these, I am also a Hodophile, a Cinephile and a foodie.

Recent Posts